BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//132.216.98.100//NONSGML kigkonsult.se iCalcreator 2.20.4//
BEGIN:VEVENT
UID:20250806T160811EDT-7222TE5rxd@132.216.98.100
DTSTAMP:20250806T200811Z
DESCRIPTION:Unfortunately\, today’ seminar is being postponed by the speake
 r for personal reasons.\n\nIt will be rescheduled as soon as possible.\n\n
  \n\nDr. Juan Ianowski\n\nAssociate Professor\, Department of Anatomy\, Ph
 ysiology and Pharmacology\, University of Saskatchewan\n\n \n\nTalk title:
  ‘’Lessons from the CFTR knockout swine: reduced airway surface liquid sec
 retion and Na+ hyperabsorption contribute to lung disease.’’\n\n \n\nUsing
  swine models of cystic fibrosis (CFTR knockout pigs) we studied the patho
 physiology of Airway Surface Liquid (ASL) secretion. We developed a synchr
 otron-based Phase Contrast Imaging (PCI) method and a high-resolution self
 -referencing Na+-selective microelectrode technique to study the mechanism
  of ASL secretion and how it malfunctions in CF. Our results suggest that 
 CF airways would fail to appropriately respond to inhaled bacteria\, resul
 ting in reduced secretion of mucin and antimicrobial factors required to c
 lear bacteria\, thus facilitating infection. Moreover\, CFTR-/- swine airw
 ay suffers from ENaC-dependent Na+ reabsorption that likely contributes to
  CF pathogenesis in the distal airways.\n\n \n\nThis seminar will be given
  online via Zoom. Details in attached poster.\n
DTSTART:20211214T210000Z
DTEND:20211214T210000Z
SUMMARY:POSTPONED - CFTRc seminar - Dr. Juan Ianowski
URL:/cftrc/channels/event/postponed-cftrc-seminar-dr-j
 uan-ianowski-335407
END:VEVENT
END:VCALENDAR