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UID:20250818T234049EDT-1048n6Ur4R@132.216.98.100
DTSTAMP:20250819T034049Z
DESCRIPTION:Zoom link:\n\n \n\nAbstract:\n\nAll known forms of life encode 
 their genetic information in a sequence of nucleobases of a genetic polyme
 r. The genetic information is propagated through replication. However\, ho
 w this process began before the advent of\, or without\, a replicase enzym
 e is unknown. This mystery in the origins of life has prompted more than 5
 0 years of research on nonenzymatic replication of a genetic material. RNA
  is a logical candidate for the primordial genetic polymer\, but significa
 nt problems associated with nonenzymatic RNA replication stifle the progre
 ss of building an abiotic system capable of Darwinian evolution (e.g. the 
 extent of copying chemistry). I will describe how using modified (RNA-like
 ) genetic polymers can circumvent certain challenges associated with RNA c
 opying chemistry\, and discuss potential routes to sustain nonenzymatic ge
 netic polymer replication. In addition\, I will discuss pathways to furthe
 r elucidate transitions from chemical processes to those that are enzymati
 c/functional.\n\nBio:\n
DTSTART:20210921T170000Z
DTEND:20210921T183000Z
LOCATION:Zoom link:
SUMMARY:Chemical Society Seminar: Derek O'Flaherty - Origins of life\; how 
 using artificial genetic polymers can overcome challenges associated with 
 nonenzymatic replication
URL:/chemistry/channels/event/chemical-society-seminar
 -derek-oflaherty-origins-life-how-using-artificial-genetic-polymers-can-33
 2903
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