BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//132.216.98.100//NONSGML kigkonsult.se iCalcreator 2.20.4//
BEGIN:VEVENT
UID:20250714T233927EDT-0688UNSs1z@132.216.98.100
DTSTAMP:20250715T033927Z
DESCRIPTION:Simon Gravel\, PhD\n\nAssistant Professor\, Human Genetics\, Mc
 Gill University\n\nPopulation structure in African-Americans\n\nALL ARE WE
 LCOME\n\nAbstract:\n\nWe present a detailed population genetic study of 3 
 African-American cohorts comprising over 3000 genotyped individuals across
  US urban and rural communities: two nation-wide longitudinal cohorts\, an
 d the 1000 Genomes ASW cohort. Ancestry analysis reveals a uniform breakdo
 wn of continental ancestry proportions across regions and urban/rural stat
 us\, with 79% African\, 19% European\, and 1.5% Native American/Asian ance
 stries\, with substantial between-individual variation. The Native America
 n ancestry proportion is higher than previous estimates and is maintained 
 after self-identified Hispanics and individuals with substantial inferred 
 Spanish ancestry are removed. This supports direct admixture between Nativ
 e Americans and African Americans on US territory\, and linkage patterns s
 uggest contact early after African-American arrival to the Americas. Local
  ancestry patterns and variation in ancestry proportions across individual
 s are broadly consistent with a single African-American population model w
 ith early Native American admixture and ongoing European gene flow in the 
 South. The size and broad geographic sampling of our cohorts enable detail
 ed analysis of the geographic and cultural determinants of finer-scale pop
 ulation structure. Recent identity-by-descent analysis reveals fine-scale 
 geographic structure consistent with the routes used during slavery and in
  the great African-American migrations of the twentieth century: east-to-w
 est migrations in the south\, and distinct south-to-north migrations into 
 New England and the Midwest. These migrations follow transit routes availa
 ble at the time and are in stark contrast with European-American relatedne
 ss patterns.\n\nBio:\n\nhttp://simongravel.lab.mcgill.ca/Home.html\n\n \n
DTSTART:20160209T203000Z
DTEND:20160209T213000Z
LOCATION:Room 24\, Purvis Hall\, CA\, QC\, Montreal\, H3A 1A2\, 1020 avenue
  des Pins Ouest
SUMMARY:Biostatistics Seminar
URL:/epi-biostat-occh/channels/event/biostatistics-sem
 inar-257706
END:VEVENT
END:VCALENDAR