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UID:20250801T192047EDT-8735Uc97Wn@132.216.98.100
DTSTAMP:20250801T232047Z
DESCRIPTION:PhD Oral Defense of Thomas Duguet\, Institute of Parasitology\n
 \nPentameric ligand-gated ion-channels (pLGICs) represent a large family o
 f transmembrane proteins that play a fundamental role in synaptic neurotra
 nsmission throughout the animal kingdom. These essential mediators of neur
 omuscular movement appeared more than two billion years ago and through th
 e central mechanism of gene duplication and loss\, have led to a diverse f
 amily of modern-day pLGICs.\n\nThe evolution of pLGICs has given rise to a
  complex population of heteromeric receptors\, particularly in the clade V
  nematode species\, closely related to the free-living model Caenorhabditi
 s elegans. Among them\, the levamisole-sensitive acetylcholine receptor (L
 -AChR) stands out\, composed of five different subunits in C. elegans. The
  appearance of new subunits of this receptor continues through gene duplic
 ation. Expansion of the unc-29 gene to four copies in the parasitic nemato
 de of small ruminants\, Haemonchus contortus\, is proposed as a model of t
 he process more generally.\n\nEveryone in the ºÚÁϲ»´òìÈ community is welcome 
 to attend a PhD oral defense. Please join us in celebrating the accomplish
 ments of our PhD candidates.\n\n \n\n \n
DTSTART:20170608T130000Z
DTEND:20170608T130000Z
LOCATION:P-117\, Parasitology Building\, CA\, QC\, St Anne de Bellevue\, H9
 X 3V9\, 21111 Lakeshore Road
SUMMARY:PhD Oral Defense: Subunit diversity of the levamisole-sensitive ace
 tylcholine receptor
URL:/macdonald/channels/event/phd-oral-defense-subunit
 -diversity-levamisole-sensitive-acetylcholine-receptor-268152
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