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UID:20250809T034206EDT-2329RbjTrR@132.216.98.100
DTSTAMP:20250809T074206Z
DESCRIPTION:\nSupported by the generosity of the Killam Trusts\, The Neuro'
 s Killam Seminar Series invites outstanding guest speakers whose research 
 is of interest to the scientific community at the MNI and ºÚÁϲ»´òìÈ Universit
 y.\n\n\nTo attend in person\, register here\n\nTo watch via vimeo\, click 
 here\n\n\nVeronique Miron\, PhD\n\nJohn David Eaton Chair\, Multiple Scler
 osis Research\, Keenan Research Centre for Biomedical Research\, St. Micha
 el's Hospital\, Canada\n\nProfessor\, Department of Immunology\, Universit
 y of Toronto\, Canada\n\nHost: rami.massie [at] mcgill.ca (R)roberta.lapia
 na [at] mcgill.ca (oberta La Piana)\n\nAbstract: Myelin is the insulation 
 surrounding axons\, which is critical for central nervous system health an
 d function\, yet it is damaged in common neurological conditions such as m
 ultiple sclerosis (MS) and pathological aging. Although myelin can be rege
 nerated in the form of remyelination\, the efficiency of this process decr
 eases with aging and the progression of MS. Our lab has discovered that gl
 ial interactions are critical in maintaining myelin health and regulating 
 remyelination post-injury. For instance\, we have seen that the absence of
  microglia is sufficient to initiate spontaneous demyelination. In additio
 n\, we have identified surprising mechanisms by which microglia support CN
 S remyelination. Here\, I will present our latest work understanding how m
 icroglia influence oligodendrocyte heterogeneity and the dynamics of myeli
 n damage and repair. This has important implications for devising novel th
 erapeutic strategies to support myelin health in aging and disease.\n
DTSTART:20240507T200000Z
DTEND:20240507T210000Z
LOCATION:de Grandpre Communications Centre\, Montreal Neurological Institut
 e\, CA\, QC\, Montreal\, H3A 2B4\, 3801 rue University
SUMMARY:Killam Seminar Series: The Disappearing Act: How Microglia Influenc
 e Myelin Health Across the Lifespan
URL:/neuro/channels/event/killam-seminar-series-disapp
 earing-act-how-microglia-influence-myelin-health-across-lifespan-354644
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