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DESCRIPTION:DR. SIEGFRIED HEKIMI\n\nProfessor\n\nDepartment of Biology\n\nM
 cGill University\n\nSeminar Title: 'Mitochondrial dysfunction\, reactive o
 xygen species\, and lifespan in animals: Untangling the knot'\n\nHost Lab:
  Trempe Lab\n\nSeminar:                 \n\nMonday\, October 2\, 2017\n\n1
 2:00pm\n\nRoom 1345\n\nMcIntyre Medical Sciences Building\n\nBrief Biograp
 hy\n\nSiegfried Hekimi was born in Zürich and obtained his undergraduate d
 egree in Biology at the University of Geneva. He then moved to the famed L
 aboratory of Molecular Biology (LMB) of the Medical Research Council in Ca
 mbridge\, UK\, to collaborate with Dr J.G. White as a post-doctoral fellow
  of the Swiss National Science Fund. It is at the LMB where Hekimi develop
 ed his interest for using 'the worm' for translational studies in the biol
 ogy of aging. It is also in Cambridge that he identified the first mutants
  that helped to demonstrate that aging could be manipulated genetically an
 d that inducing mild mitochondrial dysfunction could in fact slow down the
  aging process of animals. In 1992 he joined ºÚÁϲ»´òìÈ University where he ha
 s been a full professor since 2004.\n\n \n\nResearch expertise\n\nhttp://h
 ekimilab.mcgill.ca/\n\nWe are using mutants of the microscopic worm Caenor
 habditis elegans and the mouse  to study aging\, a crucial\, profound\, an
 d poorly understood biological phenomenon. We hope our insights will provi
 de new ways for medical intervention on the aging process. We are particul
 arly focusing on gene activities that affect mitochondrial function\, and 
 on mutants that enhance longevity. We are also interested in the biosynthe
 sis and function of ubiquinone (UQ\, Coenzyme Q\, CoQ)\, the obligate\, di
 ffusible\, relay in the mitochondrial electron transport chain. Here too w
 e use mutants in both organisms to unravel the basic biochemical functions
  of ubiquinone and to develop drugs that can help alleviate the diseases l
 inked to ubiquinone deficiency.\n
DTSTART:20171002T160000Z
DTEND:20171002T170000Z
SUMMARY:Dr. Siegfried Hekimi\, Professor Department of Biology ºÚÁϲ»´òìÈ Unive
 rsity
URL:/pharma/channels/event/dr-siegfried-hekimi-profess
 or-department-biology-mcgill-university-270621
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