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UID:20250815T213909EDT-6022PRFwwu@132.216.98.100
DTSTAMP:20250816T013909Z
DESCRIPTION:The central nervous system is inhabited by a specialized ensemb
 le of myeloid cells that are highly dynamic and survey their immediate sur
 roundings\, which include the parenchyma\, perivascular spaces\, pia mater
 \, dura mater\, and choroid plexus. These cells are long-lived\, help main
 tain homeostasis\, participate in reparative responses following injury\, 
 and protect the CNS from invading microbes. The CNS is also surveyed and s
 ometimes invaded by circulating\, blood-derived myeloid cells that can con
 tribute to diametrically opposed outcomes\, like vascular breakdown vs. re
 pair\, depending on the inflammatory context. This lecture will focus on r
 ecent developments in our understanding of CNS myeloid cells\, both reside
 nt and blood-derived. A special emphasis will be placed on how myeloid cel
 ls specifically survey and respond in different anatomical compartments\, 
 such as the dura mater\, subarachnoid space\, vasculature\, and parenchyma
 . Myeloid cell responses are customized to meet the demands of the specifi
 c anatomical niche and are guided by precise inflammatory cues. This lectu
 re will also showcase myeloid cell responses that give rise to both favora
 ble and unfavorable outcomes. \n\nThis seminar is part of the Department o
 f Physiology Friday Seminar Series and is co-sponsored by the ºÚÁϲ»´òìÈ Unive
 rsity Research Centre on Complex Traits (MRCCT).\n
DTSTART:20191115T160000Z
DTEND:20191115T170000Z
LOCATION:Room 1034\, McIntyre Medical Building\, CA\, QC\, Montreal\, H3G 1
 Y6\, 3655 promenade Sir William Osler
SUMMARY:Seminar - Immune mechanisms underlying restoration of injured CNS b
 arriers
URL:/physiology/channels/event/seminar-immune-mechanis
 ms-underlying-restoration-injured-cns-barriers-300225
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