BEGIN:VCALENDAR VERSION:2.0 PRODID:-//132.216.98.100//NONSGML kigkonsult.se iCalcreator 2.20.4// BEGIN:VEVENT UID:20250814T174654EDT-8323clN9Ci@132.216.98.100 DTSTAMP:20250814T214654Z DESCRIPTION:Differentiating pathological from physiological angiogenesis is crucial to specifically target abnormal vessel growth associated with pro liferative diseases and fostering physiological regenerative angiogenesis. This degree of selectivity is currently out of reach from anti-angiogenic therapies\, requiring a better understanding of the cell-specific identit ies of healthy and diseased vessels. Here\, we take advantage of the unpar alleled resolution provided by single-cell technologies to investigate the heterogeneity of endothelial cells and their microenvironment in a mouse model of retinal pathological angiogenesis. We identified specific subtype s of endothelial cells associated with healthy revascularization\, and not ably a rare cluster of proliferative endothelial cells present in patholog ical tissues.\n DTSTART:20191129T160000Z DTEND:20191129T170000Z LOCATION:Room 1034\, McIntyre Medical Building\, CA\, QC\, Montreal\, H3G 1 Y6\, 3655 promenade Sir William Osler SUMMARY:Seminar - Single-cell transcriptomic endothelial cell signatures of healthy and pathological vessels URL:/physiology/channels/event/seminar-single-cell-tra nscriptomic-endothelial-cell-signatures-healthy-and-pathological-vessels-3 00684 END:VEVENT END:VCALENDAR