BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//132.216.98.100//NONSGML kigkonsult.se iCalcreator 2.20.4//
BEGIN:VEVENT
UID:20250731T000453EDT-1187PBS16j@132.216.98.100
DTSTAMP:20250731T040453Z
DESCRIPTION:\n	Studies in my lab are focused on understanding the mechanisms
  by which autism-associated mutations lead to the manifestation of behavio
 ral deficits. We specifically ask how these mutations affect brain systems
  that subserve social behavior and social reward processing\, leading to i
 mpairment in social behavior. To be able to address these questions\, we u
 se a rat model with a mutation in an autism high-risk gene\, Shank3\, and 
 examine the impact of the mutation on the oxytocin and the mesoaccumbens r
 eward system\, both which play an important role in social behavior. In my
  talk\, I will provide an overview about Shank3\, its role in excitatory s
 ynapses\, its implication in autism\, and a summary of our published work 
 on the Shank3-deficient rat model. I will also share data from ongoing wor
 k in the lab that is focused on studying the impact of Shank3 mutation on 
 (1) the oxytocin system\, (2) processing social reward\, and (3) the funct
 ion of the mesoaccumbens system during social behavior. I also plan to sha
 re with the audience the challenges we faced along the way\, which opened 
 our eyes on the unique nature of the oxytocin neurons and how to best targ
 et them using viral tools.\n\nThis seminar will be offered both in-person 
 and online. Details in attached poster.\n
DTSTART:20220401T150000Z
DTEND:20220401T160000Z
LOCATION:Room 1034\, McIntyre Medical Building\, CA\, QC\, Montreal\, H3G 1
 Y6\, 3655 promenade Sir William Osler
SUMMARY:Seminar: The impact of an autism-associated mutation on brain circu
 its of social behavior
URL:/physiology/channels/event/seminar-impact-autism-a
 ssociated-mutation-brain-circuits-social-behavior-337515
END:VEVENT
END:VCALENDAR